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The cortical control of urination requires proper maturation of the nervous system in infants, in fact, urination is an act involuntary and unconscious, that occurs with purely reflex mechanism; voluntary control of the bladder sphincter starts on average at the age of two and a half years. Specifically, the act of urination is regulated by the autonomic nervous system. The sympathetic nervous system acts as an inhibitor of the detrusor and exciter of the internal sphincter, thus prompting a block of urination. Conversely, the activation process is regulated by the parasympathetic nervous system which has an antagonistic action on the two muscles. Then there is a voluntary contribution or through the motor neurons of the somatic nucleus of Onuf ( anterior horn of the spinal ) going to handle the excitement of the external sphincter. Even the abdominal muscles will shrink so that the process takes place.

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